Protein Modification Reagents
Medchemexpress LLC 4-Arm PEG-SCM MW 20 500mg
4-Arm PEG-SCM (MW 20000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery[1]
eMolecules 1609651-90-2 | ChemScene | Alkyne-PEG4-maleimide | 100mg | 686120423 | CS-0118065 | MFCD22380740 | 382.413 | C18H26N2O7
Medchem Express | BAY 2416964 | 5mg | 527574132 | HY-135829 | 2242464-44-2 | 387.820 | C18H18ClN5O3
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eMolecules 1835759-82-4 | t-Boc-Aminooxy-PEG3-acid | Broadpharm | MFCD29052175 | 337.369 | C14H27NO8 | 97.000 | CC(C)(C)OC(=O)NOCCOCCOCCOCCC(O)=O | 100mg | 296213224
t-Boc-Aminooxy-PEG3-acid | Broadpharm | 1835759-82-4 | MFCD29052175 | 337.369 | C14H27NO8 | 97.000 | CC(C)(C)OC(=O)NOCCOCCOCCOCCC(O)=O | 100mg | 296213224
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG6-CH2CH2COOH | 5 g | CAS 882847-34-9 | MDL MFCD06656474
Fmoc-NH-PEG6-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 882847-34-9
- MDL: MFCD06656474
- InChIKey: HEGZERUHBVYZPH-UHFFFAOYSA-N
- Molecular Weight: 575.655
- Molecular Formula: C30H41NO10
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
CCOCCOCCOCCN=[N+]=[N-])C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 50mg | 340377065](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1655536.jpg-250.jpg)
eMolecules 2055047-18-0 | Azido-PEG3-Val-Cit-PAB-PNP | Broadpharm | MFCD30527416 | 773.801 | C34H47N9O12 | 96.000 | CC(C)[C@H](NC(=O)CCOCCOCCOCCN=[N+]=[N-])C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 50mg | 340377065
Azido-PEG3-Val-Cit-PAB-PNP | Broadpharm | 2055047-18-0 | MFCD30527416 | 773.801 | C34H47N9O12 | 96.000 | CC(C)[C@H](NC(=O)CCOCCOCCOCCN=[N+]=[N-])C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 50mg | 340377065
Medchemexpress LLC M-PEG5-azide | 1202681-04-6 | 1 G
M-PEG5-azide is a PEG-based PROTAC linker crucial for the synthesis of PROTACs. This click chemistry reagent contains an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules. It also facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that have DBCO or BCN groups.
- Peg-based protac linker
- Used in protac synthesis
- Click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAC)
- Also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC)
Medchemexpress LLC Methyl-PEG4-NHS ester | 622405-78-1 | MFCD11041112 | 95.0% | 333.33 | C14H23NO8 | 10G
Methyl-PEG4-NHS ester is a methyl-capped polyethylene glycol linker terminating in an N-hydroxysuccinimide (NHS) ester. It is used for amine-targeted bioconjugation and as a flexible PEG spacer in bifunctional molecules, enabling efficient formation of stable amide bonds and improved solubility.
- Provides an NHS ester for rapid conjugation to primary amines.
- Methyl-capped PEG4 spacer increases solubility and linker flexibility.
- Suitable for PROTAC synthesis and general bioconjugation applications.
- Molecular weight 333.33 and molecular formula C14H23NO8.
- CAS number 622405-78-1 and MFCD11041112 for reference.
- Typical purity around 95.0% and available in multiple pack sizes.
Medchemexpress LLC DSPE-PEG5000 maleimide ammonium salt | 474922-22-0 | 98.4% | (C2H4O)nC51H92N1O13P.H3N | 10MG
DSPE-PEG5000-Mal is a lipid-polyethylene glycol conjugate bearing a terminal maleimide group for selective thiol coupling. It integrates into lipid bilayers to functionalize liposomes and lipid nanoparticles, while the PEG5000 chain provides steric stabilization and extended circulation in biological media.
- Maleimide-functional group enables selective thiol conjugation.
- PEG5000 chain provides steric stabilization and prolongs circulation time.
- Phospholipid anchor integrates into lipid bilayers and nanocarriers.
- High reported purity supports reproducible formulation performance.
- White to off-white solid suitable for analytical handling and storage.
![eMolecules 2354291-37-3 | Gly-PEG3-endo-BCN | Broadpharm453.580 | C23H39N3O6 | 0.000 | NCC(=O)NCCCOCCOCCOCCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 100mg | 550804569](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183536.JPG-250.jpg)
eMolecules 2354291-37-3 | Gly-PEG3-endo-BCN | Broadpharm453.580 | C23H39N3O6 | 0.000 | NCC(=O)NCCCOCCOCCOCCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 100mg | 550804569
Gly-PEG3-endo-BCN | Broadpharm | 2354291-37-3453.580 | C23H39N3O6 | 0.000 | NCC(=O)NCCCOCCOCCOCCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 100mg | 550804569
Medchemexpress LLC Biotin-PEG4-TFP ester | 2985664-57-9 | MFCD27952880 | 98.2% | C27H37F4N3O8S | 10MG
Biotin-PEG4-TFP ester is a biotinylated PEG4 spacer terminated with a tetrafluorophenyl (TFP) activated ester, formulated for conjugation to primary amines in proteins, peptides, or small molecules. It enables rapid formation of stable amide bonds while providing a hydrophilic linker that reduces steric hindrance and improves solubility. The TFP activated ester offers greater hydrolytic stability than many NHS esters, supporting cleaner bioconjugation and linker assembly workflows.
- Activated TFP ester for efficient coupling to primary amines.
- Biotin tag for affinity capture and detection.
- PEG4 spacer improves solubility and reduces steric hindrance.
- Greater hydrolytic stability than many NHS esters, enabling cleaner conjugations.
- Suitable for protein, peptide, and small-molecule conjugation applications.
Medchemexpress LLC m-PEG-azide (MW 5000) | 98.0% | COCCOCCN=[N+]=[N-].[n].[MW 5000] | 50 MG
m-PEG-azide (MW 5000) is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker.
- Click chemistry reagent.
- Contains an Azide group.
- Can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc).
- Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions.
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG5-CH2COOH | 25 g | CAS 635287-26-2 | InChIKey LNIFRTLAPAPKAG-UHFFFAOYSA-N
Fmoc-NH-PEG5-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 635287-26-2
- MDL: No data
- InChIKey: LNIFRTLAPAPKAG-UHFFFAOYSA-N
- Molecular Weight: 517.575
- Molecular Formula: C27H35NO9
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid
- SMILES: O=C(COCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
eMolecules 2183440-36-8 | APN-C3-PEG4-alkyne | Broadpharm469.538 | C25H31N3O6 | 97.000 | O=C(CCOCCOCCOCCOCC#C)NCCCC(=O)Nc1ccc(cc1)C#CC#N | 5mg | 374905429
APN-C3-PEG4-alkyne | Broadpharm | 2183440-36-8469.538 | C25H31N3O6 | 97.000 | O=C(CCOCCOCCOCCOCC#C)NCCCC(=O)Nc1ccc(cc1)C#CC#N | 5mg | 374905429
(=O)OCCNC(=O)OCCOCC(=O)NCc1ccc(cc1F)B(O)O)OC(=O)CCCCCCCCCCCCCCCCC | 100mg | 718091659](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502474728.jpg-250.jpg)
eMolecules DSPE-PEG-Boronate, MW 3,400 | Broadpharm |1045.130 | C53H95BFN2O14P | 98.000 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCNC(=O)OCCOCC(=O)NCc1ccc(cc1F)B(O)O)OC(=O)CCCCCCCCCCCCCCCCC | 100mg | 718091659
DSPE-PEG-Boronate, MW 3,400 | Broadpharm |1045.130 | C53H95BFN2O14P | 98.000 | CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCNC(=O)OCCOCC(=O)NCc1ccc(cc1F)B(O)O)OC(=O)CCCCCCCCCCCCCCCCC | 100mg | 718091659
Enzo Life Sciences Gefitinib-based PROTAC 3 (1mg). CAS: 2230821-27-7
Gefitinib-based PROTAC 3 is targeting on EGFR, consisting of Gefitinib as the warhead linked to VHL-recruiting ligand. Purity: ≥99%. Solubility: Soluble in DMSO (75 mg/mL). Insoluble in water. Long Term Storage: -20°C.